اجسام هاينز , دم

Heinz bodies are formed by damage to the Hemoglobin component molecules, usually through oxidations, which causes the damaged molecules to precipitate and damage the cell membrane. Damaged cells are attacked by macrophages in the spleen, where the precipitated and damaged membrane is removed, leading to characteristic “bite cells”. The denaturing process is irreversible and the continual elimination of damaged cells leads to Heinz body anemia.

G6PD (Glucose-6-Phosphate Dehydrogenase) deficiency brought on by administration of oxidant drugs (e.g., primaquine) also can result in Heinz bodies.

1 ml EDTA Whole Blood Room Temperature

Usually invisible with Wright’s stain.

سلبي (Negative)