Quantiferon Gold-Mycobacterium tuberculosis (TB)

The antigens used in QFT-Plus are a peptide cocktail simulating the proteins ESAT-6 and CFP-10. Numerous studies have demonstrated that these peptide antigens stimulate IFN-Ȣ responses in T cells from individuals infected with M. tuberculosis, but generally not from uninfected or BCG vaccinated persons without disease or risk for LTB (1-32).
However medical treatment or conditions that impair immune functionality can potentially reduce IFN-Ȣ responses. Patients with certain other mycobacterial infections might also be responsive to ESAT-6 and CFP-10 as the genes encoding these proteins are present in M. kansasii, M. marinum (1, 23). QFT-plus is both a test for LTB1 and a helpful aid for diagnosing M. tuberculosis complex infection in sick patients. A positive result supports the diagnosis of tuberculosis disease, but infections by other mycobacteria (e.g M.kansaii) could also lead to positive results. Other medical and diagnostic evaluations are necessary to confirm or exclude tuberculosis disease.

QuantaFERON -TB-Gold test is ablood test usesd to detect latent or active tuberculosis (TB) infectionby measuring the immune response to Mycobacterium tuberculosis antigens.

1 ml plasma samples harvested from special blood collection tubes. 28 days at 2-8 °C for extended period store at -20 °C.

<0.35 IU/ml