17-Hydroxy Progesterone, Serum


17-Hydroxy-Progesterone (17-OHP) is a steroid secreted by the adrenal glands and gonads. Its precursors are 17-hydroxy-pregnenolone and progesterone. 17-Hydroxy-Progesterone is converted to cortisol in the adrenal glands and to androstenedione (testosterone precursor) and estradiol in the ovaries and adrenals. It has an ACTH-dependent diurnal variation with higher levels in the morning and lower levels at night. See also 17-Hydroxy Pregnenolone, Serum

دواعي الإستعمال

Increased 17-Hydroxy-Progesterone levels are associated with 21-hydroxylase and 11-β Hydroxylase deficiency, the most common causes of congenital adrenal hyperplasia, and certain adrenal and ovarian tumours. The test is also used in monitoring steroid replacement therapy.

نوع العينة والكمية والشروط

1 ml Serum Stability: 12 Hours at 2-8 °C 30 Days at -20 °C

إحتياطات خاصة

Due to diurnal variation, sample collection time should be noted and standardised.

المعدل الطبيعي

Male (1 Month): 0.0-8.0 ng/mL Female (1 Month): 2.4-16.8 ng/mL Male (2 Months): 3.6-13.7 ng/mL Female (2 Months): 1.6-9.7 ng/mL Male (3 Months): 1.7-4.0 ng/mL Female (3 Months): 0.1-3.1 ng/mL Children (3-14 Years): 0.07-1.7 ng/mL Adult Female: Follicular Phase: 0.1-0.8 ng/mL Luteal phase: 0.6-2.3 ng/mL Ovulatory Period: 0.3-1.4 ng/mL Post ACTH: < 3.2 ng/mL Late Pregnancy: 2.0-12.0 ng/mL Menopause: 0.13-0.51 ng/mL Adult Male: 0.5-2.1 ng/mL

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