Cardiolipin Antibodies, IgG, Serum

Anti cardiolipin antibodies are a heterogeneous group of autoantibodies of the IgG, IgM and IgA classes directed against phospholipids. These autoantibodies occur in a variety of disorders such as primary anti phospholipid antibody syndrome, systemic lupus erythematosus (SLE), and in some apparently healthy subjects. See Also Anti phospholipid Antibodies, β-Beta-2-Glycoprotein 1 Antibodies, Lupus Anticoagulant and ANA

Anti cardiolipin antibodies are mainly associated with thrombosis, thrombocytopenia, and spontaneous abortion. Correlations are strongest with anti cardiolipin IgG antibodies, which are apparently specific for β-2-glycoprotein 1 complexed to negatively charged phospholipids. These autoantibodies demonstrate cross reactivity with cardiolipin components of other test reagents such as VDRL and RPR causing false positive results.

1 ml Serum Stability: 2 Days at 2-8 °C

Negative: < 10 U/ml Positive: ≥ 10 U/ml