Hemoglobin Pattern Analysis


The type of Hemoglobin that an individual has is determined by the emoglobin gene that they have inherited from both their parents. The normal adult Hemoglobin which predominates in individuals over the age of one year is called Hemoglobin ‘A’ (HbA). It is made up of a pair of α and a pair of β chains. Synthesis of the β chain is controlled by the β globin gene located on chromosome 11, whilst production of α chains is controlled by the α globin gene located on chromosome 16. The β gene is expressed once on each of chromosome 11 but the α gene is expressed twice on each of chromosome 16 and therefore synthesises a double amount of β chains. Hemoglobinopathies refers to a range of genetically inherited disorders of Hemoglobin and includes sickle cell disease and thalassaemias.

دواعي الإستعمال

This is a semiquantitative test used for the diagnosis of Hemoglobinopathies including thalassaemias, sickle cell anaemia, the detection of Hemoglobins C, D, E, F and other rare types of Hemoglobins.

نوع العينة والكمية والشروط

2 ml EDTA Whole Blood Stability: 4 Days at 2-8 °C

إحتياطات خاصة

HPLC is the primary test methodology and Alkaline and acid electrophoresis are performed for confirmation purposes. Blood transfusions may give false or inconsistent results.

المعدل الطبيعي

HbA: 94.0 - 98.5 % Hb A2 1.5 - 3.5 % Hb F: up to 2.0 % Hb S: Negative Hb C: Negative Hb D: Negative

Scan the code
Hello 👋
هل يمكننا مساعدتك؟