Proteinase 3 (PR3) Antibodies, Serum

Used for the diagnosis and monitoring of inflammatory activity in primary systemic small vessel vasculitides. The presence of anti-PR3 antibodies is highly specific for Wegener granulomatous (WG) disease, for which the sensitivity is reported to be 98%. Some patients with WG have P-ANCA with MPO specificity. Levels of anti-PR3 or anti-MPO are elevated during the active phases of the disease and lower during remission and can be monitored for management of the disease. See Also Neutrophil Cytoplasmic Antibodies (ANCA), Serum

1 ml Serum Stability: 14 Days at 2-8 °C

Negative