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What We Do & Why We Do It

EtioLabs are a new private diagnostics laboratory, based in Dublin and headquartered in Westmeath, Ireland. We were founded in September 2024 in response to the testing backlog in Ireland caused by the Covid-19 pandemic in 2020.

EtioLabs is primed to revolutionise the Irish healthcare industry through comprehensive, timely, and affordable testing solutions, driving down costs, wait times and improving outcomes for all.

Benjamin Franklin said in 1736, “An ounce of prevention is worth a pound of cure” and this proverb is as relevant today as ever. In Ireland, where timely access to healthcare is often challenged by long waiting lists, disease prevention isn’t just a principle — it’s a necessity.

At EtioLabs, we live by the principle that behind every test result is a life, a family, and a future depending on our accuracy and every hour saved is a life improved. Faster testing means earlier action. Earlier action means better outcomes. And better outcomes mean stronger, healthier communities, not just here in Ireland, but across the world.

Our Vision. Mission and Values:

At EtioLabs our vision is to revolutionise healthcare testing services in Ireland. We are committed to offering efficient, reliable, and cutting-edge testing solutions that cater to the unique needs of healthcare providers and patients. Our mission is to become the leading private testing laboratory in Ireland, to be an integral partner in the Irish healthcare landscape, contributing to improved diagnostics, timely treatment, and overall healthcare outcomes.

What’s in a Name?

The name Etio comes from the origin ‘Etiology’ which refers to the ‘cause or origin of a disease or a condition’. In a broader context, etiology can also refer to the study of causes in general — not just for diseases, but also for behaviors or events. We chose the name Etio because we want to position ourselves as a healthcare brand that gets to the root of medical & health problems, finds the cause and enables patients, insofar as is possible, to fix them. We believe that the path to great health is through patient advocacy, disease monitoring, and ongoing access to world-class advice and support. All illness has a root cause that must be identified. We don’t believe in sticking plasters on chronic disease, rather in the identification of markers and red flags well before symptoms manifest.

EtioLabs…getting to the root of great patient health

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In 1937, the Turkish dermatologist and scientist Hulusi Behçet observed several patients visiting his clinic with general symptoms such as mouth and genital ulcers, uveitis (inflammation of the middle layer of the eye), and erythema nodosum. These observations eventually led to the identification of this syndrome, which was later named after him. In this article, we will explore this condition, its symptoms, and how to manage them.

What is Behçet’s Syndrome?

First, what does the term syndrome mean? It is a medical term used to describe a group of symptoms and clinical signs that occur together and are characteristic of a specific disease.

Behçet’s Syndrome is an autoimmune condition of unknown exact cause that affects blood vessels, leading to their inflammation and swelling, along with general inflammatory reactions throughout the body. Patients often visit their doctor complaining of recurrent oral and genital ulcers or painful eye inflammation. Upon examination, widespread vasculitis (inflammation of the blood vessels) is often found, allowing physicians to diagnose the condition based on the combination of symptoms.

What Are the Causes of Behçet’s Disease?

Like other autoimmune diseases, the exact cause of Behçet’s Syndrome is not fully understood, but genetic and environmental factors are believed to play a major role. It is more common among individuals from regions stretching from East Asia to the Eastern Mediterranean, including Central Asia, Iran, and Turkey.

Carrying the HLA-B51/B5 gene—which is common among Japanese, Middle Eastern, and Turkish populations—also significantly increases the risk of developing Behçet’s Disease, clearly indicating the interaction between genetic predisposition and environmental triggers in its development.

Ongoing research continues to investigate the precise causes and contributing factors of this disease. While several additional genetic and immune-related factors have been identified, their exact relationship to the onset of Behçet’s Disease remains a topic of scientific debate and study.

What Are the Symptoms of Behçet’s Disease?

As mentioned earlier, the symptoms of Behçet’s Disease are often general and non-specific, making it difficult to pinpoint the underlying cause at first. Since the initial signs often include skin ulcers and eye inflammation, patients may first consult a dermatologist or an ophthalmologist, as the symptoms resemble other common conditions, this can lead to delayed diagnosis. The main symptoms of the disease include:

• Oral, genital, and skin ulcers: These appear in most patients and are usually the first clinical sign of the disease.

• Eye inflammation: Patients may experience painful eye redness and blurred vision.

• Joint pain: Some may suffer from joint pain, stiffness, or swelling.

• Inflammation of blood vessels: Behçet’s can affect blood vessels of all sizes, most commonly causing superficial and deep vein thrombophlebitis in the lower limbs.

• Inflammation in other organs: In some cases, the disease may involve the nervous system, digestive tract, or heart, leading to additional complications.

How Is Behçet’s Syndrome Diagnosed?

There is no single test that can confirm Behçet’s Syndrome. Diagnosis mainly depends on the pattern and recurrence of symptoms. However, the doctor may request certain laboratory and imaging tests to support the diagnosis and rule out similar diseases. These may include:

• Urine and blood tests: To check for inflammation in the body and rule out other autoimmune diseases such as Systimic Lupus or Crohn’s disease.

• Imaging tests (X-rays or MRI scans): To detect signs of vascular inflammation or organ involvement.

• Pathergy test: This test is not definitive but supportive. The doctor pricks the patient’s skin with a sterile needle; if a red bump or pustule develops within 24–48 hours, it indicates increased skin sensitivity, which is characteristic of Behçet’s Disease.

A diagnosis is confirmed based on clinical findings, usually if two or more characteristic symptoms are present with oral ulcers recuring more than three times per year a patient can get a definite diagnosis of BD.

Can Behçet’s Disease Be Treated?

There is no permanent cure for Behçet’s Disease; however, treatment primarily aims to control symptoms and reduce inflammation. Doctors often prescribe immunosuppressive medications to help calm the immune system, along with topical creams or ointments to treat skin ulcers. Corticosteroids may be used to relieve inflammation affecting various organs, while eye drops are given to reduce eye inflammation and prevent complications. 

In cases where these medications fail to provide adequate relief, physicians may turn to biological treatment for Behcet Disease, which works by targeting specific immune pathways to suppress inflammation. Biologic therapy is not a single medication but a group of advanced treatments, and the choice of drug depends on the patient’s condition and the severity of the disease.

FAQs:

• What Is Behçet’s Disease and Is It Dangerous?

Behçet’s Disease is a chronic autoimmune disorder that causes inflammation in blood vessels of all sizes. This leads to recurrent mouth and genital ulcers, as well as inflammation affecting the eyes, joints, skin, and sometimes the nervous or digestive systems. The disease is chronic and fluctuating, meaning it alternates between periods of activity and remission. It is not considered dangerous in all cases, but in some patients, it can cause serious complications—especially when inflammation affects the eyes or major blood vessels.

• Is Behçet’s Disease Fatal?

Behçet’s Disease is generally not fatal, and most patients live normal lives with proper treatment and regular medical follow-up. However, in severe cases involving major blood vessels—particularly the pulmonary artery—or when there is significant inflammation of the central nervous system, the disease can become life-threatening. Such complications are rare but serious, making early diagnosis and consistent monitoring essential to prevent them.

• Does Behçet’s Disease Affect the Heart?

Yes, Behçet’s Disease can affect the heart, although this is uncommon. Possible cardiac complications include pericarditis (inflammation of the membrane surrounding the heart), myocarditis (inflammation of the heart muscle), endocarditis (inflammation of the inner lining of the heart), and sometimes inflammation or aneurysm of the coronary arteries. These conditions require close monitoring and treatment with anti-inflammatory or immunosuppressive medications under the supervision of a rheumatologist or cardiologist.