Acetaminophen (Paracetamol), Serum


Paracetamol is a widely used analgesic and antipyretic.


Paracetamol overdose could result in liver failure. The best indication of acetaminophen toxicity is measurement of the drug half-life by analysing a blood level taken 6 hours post ingestion, then a second level 3-4 hours later. Half-lives exceeding 4 hours are consistent with hepatic necrosis. Hepatic and renal toxicity may occur at therapeutic doses in alcoholics.

Sample Type, Quantity & Conditions

1 ml Serum Room Temperature

Special Precautions

Usual sampling time is one hour after dose administration. Time to peak serum concentration is between 30 minutes and one hour after oral dose administration. Note: Indicate Trough or Peak.

Normal Range

Theraputic Level: 10.0 - 30.0 ug/ml Toxic Level: > 150 ug/ml

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