Adrenal Antibodies, Serum


Tests for adrenal antibodies are used to diagnose autoimmune adrenal insufficiency. The term adrenal antibodies refers to several different autoantibodies that are directed against the adrenal cortex, the outer layer of tissue surrounding each of the adrenal glands. Adrenal antibodies are also known as adrenocorticol antibodies or, more accurately, adrenocorticol autoantibodies (ACA). ACA destroy adrenal tissue, interfering with hormone production, by damaging various adrenal proteins. See Also ACTH, Aldosterone & Cortisol


Primary adrenocortical insufficiency mainly occurs due to autoimmune adrenalitis with an incidence of 44-94%. Other causes include disorders such as infectious adrenalitis, neoplastic diseases, metastasis of cancers & lymphomas, adrenal hemorrhage and thrombosis, drug-induced, genetic and neonatal maternal Cushing's syndrome or trauma. Adrenal antibodies are also useful in the differential diagnosis of Addison's disease.

Sample Type, Quantity & Conditions

1 ml Serum Room Temperature

Special Precautions

Normal Range

Negative: < 1/10 Titre

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