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Albumin, Serum/Plasma

Description

Albumin is a non-glycosylated (carbohydrate free) protein with a molecular weight of 66 KD. It is synthesised in the parenchymal cells of the liver and constitutes 55-65% of total serum or plasma protein. Albumin maintains oncotic plasma pressure and is involved in the transport of a wide variety of ligands and compounds found in the circulation. Albumin is also capable of binding toxic heavy metals and medicinal drugs.

Indications

Hypoalbuminemia is caused by liver disease, malnutrition, severe burns,inflammation, malabsorption due to inflammatory bowel disease, nephrotic syndrome, and protein loss via the stool in neoplastic disease. Hyperalbuminemia is only of importance in cases of dehydration.

Sample Type, Quantity & Conditions

1 ml Serum 1 ml Li-Heparin or K2-EDTA Plasma Stability: 2.5 Months at 20-25 °C 5 Months at 4-8 °C 4 Months at -20 °C

Special Precautions

Avoid prolonged tourniquet use.

Normal Range

Newborn (0-4 Days): 2.8 - 4.4 g/dL Children (4Days - 14 Years): 3.8 - 5.4 g/dL Adult : 3.5 - 5.2 g/dL

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