Arylsulphatase A, Blood


Arylsulphatase A is an enzyme involved in the normal catabolism of cerebroside sulphatide. The arylsulphatase A gene, located on chromosome 22, has a few common mutations causing enzyme deficiency which result in juvenile and adult onset Metachromatic Leucodystrophy (MLD), a neurodegenerative lysosomal storage disease, in addition to psuedoarylsulphatase deficiency. MLD, in its severe form, presents in the first 2 years of life with spastic paraparesis and developmental delay whereas in the adult form it is associated with dementia and behavioural problems.


Useful in the diagnosis of MLD.

Sample Type, Quantity & Conditions

10 ml Heparin Blood Room Temperature

Special Precautions

Due to instability, draw sample as close to testing date as possible.

Normal Range

By Report

Open chat
Scan the code
Hello 👋
Can we help you?