Description
B- type natriuretic peptide (BNP) is a cardiac neuro-hormone secreted from the ventricles in response to volume expansion and pressure overload. In general, BNP has a natriuretic and vasodilatory effect and suppresses the renin-angiotensin- aldosterone system.
Indications
BNP is a highly sensitive and specific marker for left ventricular dysfunction and is used to follow up ventricular function in response to medical management. BNP determinations have shown the potential to be a good prognostic marker for morbidity and mortality in patients with heart failure, including predicting future cardiac events in patients with acute exacerbation. BNP appears to have clinical utility in excluding a diagnosis of heart failure in patients with symptoms of breathlessness or fluid retention.
Sample Type, Quantity & Conditions
1 ml EDTA Plasma Stability: 4 Hours at Room Temperature 24 Hours at 2-8 °C 3 Months at -20 °C
Special Precautions
Avoid grossly haemolysed samples.
Normal Range
< 100 pg/mL
