Description
Brucellosis, one of the five common zoonotic infections with world-wide distribution that is endemic in the Mediterranean region, the Middle East, Central Asia, and parts of Africa and Latin America, is caused by gram-negative, non-motile, nonspore forming, facultative intracellular coccobacilli belonging to the genus Brucella. The disease has a wide spectrum of clinical manifestations and can affect a variety of organs and systems. Localised and complicated forms of brucellosis cause morbidity and require prolonged medical treatment. Mortality is relatively low and is related mainly to cardiovascular and central nervous system complications of the disease.
Indications
The detection of Brucella specific antibodies of the IgG class is useful in the diagnosis of brucellosis and indicates current or past infection. Antibodies of the IgG class but not the IgM class are increased during relapse.
Sample Type, Quantity & Conditions
1 ml Serum Stability: 7 Days at 2-8 °C
Special Precautions
Draw sample during the first week of illness and then 3-4 weeks later.
Normal Range
Negative: < 9.0 Index Borderline: 9.0 - 11.0 Index Positive: > 11.0 Index
