Cortisol, Free, 24 Hrs Urine


See Also Cortisol, Serum


Urinary free cortisol is proposed as a test of adrenal function. It is considered the best screening test of endogenous hyper-cortisolism, assuming complete collection of urine. The test has superseded measurements of the excretion of 17-hydroxy-corticosteroids and 17-ketosteroids, which are dependent on body weight and creatinine clearance, and are less sensitive. Increased urinary free cortisol levels have been reported in patients with essential hypertension.

Sample Type, Quantity & Conditions

30 ml of 24 Hrs Urine Room Temperature

Special Precautions

State 24 Hrs urine volume. Boric acid is an acceptable preservative. Avoid samples preserved with HCl or acetic acid. If samples are collected without preservative they should be frozen immediately.

Normal Range

3.5 - 45.0 µg/24 Hrs

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