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Coxsackie Virus (A7, 9, 16 & 24) Antibodies, IgG, Serum

Description

Coxsackie viruses are small non-enveloped RNA viruses grouped in the human Enterovirus genus of the Picornaviridae family. Coxsackieviruses are associated with a wide range of human diseases such as meningitis, encephalitis, paralysis, myocarditis, pleurodynia, exanthemas, respiratory illnesses, acute hemorrhagic conjunctivitis, hand, foot, and mouth disease and juvenile-onset diabetes. Division of virus types into A and B subgroups depends on the disease signs and histopathological lesions that occur after inoculation into new-born mice.

Indications

The detection of anti coxsackie virus antibodies indicates past of recent exposure to the virus. Rising coxsackie specific IgG antibody titres and/or the detection of specific IgM antibodies are suggestive of current infection with the virus.

Sample Type, Quantity & Conditions

2 ml Serum Room Temperature

Special Precautions

Serum should be collected at onset of disease and then 2-4 wks later to determine acute and convalescent titres.

Normal Range

Negative: < 1/10 Titre

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