Description
Coxsackie viruses are small non-enveloped RNA viruses grouped in the human Enterovirus genus of the Picornaviridae family. Coxsackieviruses are associated with a wide range of human diseases such as meningitis, encephalitis, paralysis, myocarditis, pleurodynia, exanthemas, respiratory illnesses, acute hemorrhagic conjunctivitis, hand, foot, and mouth disease and juvenile-onset diabetes. Division of virus types into A and B subgroups depends on the disease signs and histopathological lesions that occur after inoculation into new-born mice.
Indications
The detection of anti coxsackie virus antibodies indicates past of recent exposure to the virus. Rising coxsackie specific IgG antibody titres and/or the detection of specific IgM antibodies are suggestive of current infection with the virus.
Sample Type, Quantity & Conditions
2 ml Serum Room Temperature
Special Precautions
Serum should be collected at onset of disease and then 2-4 wks later to determine acute and convalescent titres.
Normal Range
Negative: < 1/10 Titre