Endomysial Antibodies IgA, Serum


Endomysial antibodies are autoantibodies of the IgA, IgG or IgM class directed against the endomysium and are mainly associated with celiac disease. See Also Gliadin,Reticulin, and Tissue Transglutaminase Antibodies


Endomysial IgA Antibodies are highly specific for celiac disease (CD) or gluten-sensitive enteropathy with an incidence of around 100%. However, according to the criteria of the European Society for Paediatric Gastroenterology and Nutrition, serum must be positive for antibodies to at least two of Endomysial, Gliadin, and Reticulin to diagnose CD. The test is useful in monitoring CD patients; these antibodies generally decrease or become negative in patients on gluten-free diets and will usually reappear upon gluten challenge. These antibodies are also specific for dermatitis herpetiformis with an incidence of around 70%.

Sample Type, Quantity & Conditions

1 ml Serum Stability: 14 Days at 2-8 °C

Special Precautions

Normal Range

Negative: < 1/10 Titre

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