Description
Celiac disease (CD) reflects intolerance to gliadin (a component of gluten found in wheat) and related proteins from rye and barley. Affected children suffer from failure to thrive, diarrhoea and malabsorption whereas adults present with dermatitis herpetiformis, abdominal pain, and anaemia. Patients with CD usually have circulating antibodies against gliadin, reticulin, endomysium and tissue transglutaminase. See Also Gliadin Antibodies, IgG, Reticulin Antibodies, IgA & IgG,
Endomysial Antibodies and Tissue Transglutaminase Antibodies
Indications
Gliadin antibodies, both IgA and IgG, have been used (along with anti reticulin, endomysial and tissue transglutaminase antibodies) in the diagnosis of CD. Gliadin antibodies of the IgA class have a sensitivity and specificity of 70-100% for predicting CD.
Sample Type, Quantity & Conditions
1 ml Serum Stability: 14 Days at 2-8 °C
Special Precautions
Normal Range
Negative: < 12.0 U./ml Positive: ≥ 12.0 U./ml
