Globulin, Serum/Plasma


Globulin is one of the two types of serum proteins, the other being albumin. This generic term encompasses a heterogeneous series of families of proteins (α-1 globulins, α-2 globulins, β-globulins and ɣ- globulins), with larger molecules and less soluble in pure water than albumin, which migrate less than albumin during serum electrophoresis. See Also Protein, Total, Serum


Increased in chronic liver disease and in paraproteinaemias where a specific immunoglobulin is increased. Decreased in nephrotic syndrome, malnutrition and hypogammaglobulinaemia.

Sample Type, Quantity & Conditions

1 ml Serum 1 ml Li-Heparin or K2-EDTA Plasma Stability: 1 Month at 2-8 °C 4 Months at (-15)-(-25) °C

Special Precautions

Normal Range

2.0 - 3.5 g/dL 20 - 35 g/L

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