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Influenza Virus Strain A Antibodies, IgG, Serum

Description

Influenza viruses are enveloped RNA viruses belonging to the family Orthomyxoviridae. These viruses are classified into three types A, B, and C based on their core proteins. Influenza A and B possess two surface glycoproteins, neuraminidase (NA) and haemagglutinin (HA), which are capable of stimulating immune responses in humans. Strains are classified according to the types of their NA, and HA types, 9 and 15 respectively. Only HA types 1, 2, and 3 have established stable lineages in humans. Influenza A is usually responsible for pandemics and annual outbreaks while Influenza B is more stable causing outbreaks every 2-4 years. Influenza is spread via nasal and respiratory secretions. The short incubation period (2-3 days) and high viral titres contribute to the rapid spread of outbreaks.

Indications

The detection of Influenza specific IgG antibodies indicates recent or past infection. These antibodies, however, do not incur immunity; Influenza viruses undergo antigenic change (drift) and as a result are capable of evading humoral immunity and reinfecting the host.

Sample Type, Quantity & Conditions

1 ml Serum Room Temperature

Special Precautions

Normal Range

Negative: <1/10 Titre

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