Neuron-Specific Enolase (NSE), Serum


Neuron-specific enolase (NSE) is an acidic soluble protein, which functions as a glycolytic isoenzyme and is predominantly present in neurones, neuroendocrine cells, and neuroendocrine tumours.


NSE is used as a marker for neuroblastoma, small-cell lung cancer, amine precursor uptake and decarboxylation (APUD) cell tumours including islet-cell tumours, pheochromocytomas, medullary thyroid carcinomas, oat-cell tumours, and APUDomas of the gut, pancreas, and lung. NSE could be of potential use as a prognostic marker for destructive processes in the CNS. In addition, it can be used to monitor the course of ischemic stroke, subarachnoid haemorrhage, or severe head injury.

Sample Type, Quantity & Conditions

1 ml Serum Room Temperature

Special Precautions

Normal Range

16.3 ng/ml

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