Platelets Antibodies, Serum

Adult Autoimmune Thrombocytopeniac Purpura (ATP) is a platelet disorder that develops in certain individuals with a genetic as well as sex (female) predisposition following an environmental event. This results in the production of an IgG antiplatelet antibody capable of reacting with the host’s platelets, as well as across the placenta. This leads to the rapid clearance and destruction of opsonised platelets by the reticuloendothelial system, particularly the spleen, by greater than ten-fold the normal rate.

The platelet antibody detection test is designed to find platelet specific antibodies. Alloantibodies are associated with Immune Thrombocytopenic Purpura (ITP), Neonatal Alloimmune Thrombocytopenia (NAT). Platelet- bound lgG correlates with disease severity, whereas serum anti-platelet IgG does not.

1 ml Serum Room Temperature

Negative