Prostatic-Specific Antigen (PSA) Free/Total, Ratio


This is a simple calculation of the ratio of free unbound PSA to protein-bound PSA. See Also Prostate-Specific Antigen Total & Free, Serum


The lowered proportion of free PSA in patients with prostate cancer is expressed as a decrease in the F/T PSA ratio. However, the diagnostic value of using F/T PSA ratio is of relevance in patients with a total PSA between 4-10 ng/ml. In patients with PSA levels <4.0, use of ratio could be misleading.

Sample Type, Quantity & Conditions


Special Precautions

Normal Range

Suggestive of Neoplasia: < 10 % Gray Zone: 10-20 % Normal or B.P.H.: > 20 %

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