Skin Antibodies, Serum

Autoimmune bullous disorders are a group of severe skin diseases that are characterised clinically by blisters and erosions of skin and/or mucous membranes and serologically by the presence of autoantibodies that target distinct adhesion molecules of the epidermis, dermoepidermal basement membrane zone and anchoring fibrils of the dermis. Based on the specificity of the target antigens, several clinically and serologically distinct bullous disorders have been defined; Pemphigus vulgaris (PV), bullous pemphigoid (BP), bullosa acquisita and dermatitis herpetiformis.

This test is useful in the diagnosis of bullous disorders. The incidence of skin antibodies in the sera of affected individuals ranges from 70 - 90%.

1 ml Serum Room Temperature

Negative