Vitamin H (Biotin), Serum


Biotin, an essential water-soluble vitamin, Also known as Vitamin B8, is the coenzyme for five carboxylases in humans. These carboxylases are involved in amino acid catabolism, fatty acid synthesis and gluconeogenesis. In its action as a coenzyme, biotin becomes covalently attached to these carboxylases. Symptoms associated with biotin deficiency include, scaly dermatitis, pallor, irritability, anorexia, nausea and hair loss. In addition, altered immune status may occur as a result of biotin deficiency. See Also Biotinidase, Quantitative, Serum


Biotin deficiency occurs in patients with Leiner’s disease and in patients with biotinidase and carboxylase deficiency. In addition, biotin deficiency can occur in patients with short small intestine.

Sample Type, Quantity & Conditions

2 ml EDTA Plasma Room Temperature

Special Precautions

Normal Range

0.82-2.87 nmol/L

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