الصفائح الدمويه , اجسام مضاده , مصل

Adult Autoimmune Thrombocytopenia Purpura (ATP) is a platelet disorder
that develops in certain individuals with a genetic as well as sex (female)
predisposition following an environmental event. This results in the
production of an IgG antiplatelet antibody capable of reacting with the host’s
platelets, as well as across the placenta. This leads to the rapid clearance
and destruction of opsonised platelets by the reticuloendothelial system,
particularly the spleen, by greater than tenfold the normal rate.

The platelet antibody detection test is designed to find plateletspecific antibodies. Alloantibodies are associated with Immune Thrombocytopenia Purpura (ITP), Neonatal Alloimmune Thrombocytopenia (NAT). Platelet- bound lgG correlates with disease severity, whereas serum anti-platelet IgG does not.

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سلبي (Negative)