Delta Aminolevulinic Acid (DALA), Urine


Delta aminolevulinic acid (DALA) is an intermediate in the biosynthesis of porphyrin and is a precursor in haem synthesis. haem synthesis abnormalities due to ALA dehydretase deficiency and Lead poisoning, lead to the accumulation of DALA, which results in abnormal pharmacological and neurological effects and symptoms. These include abdominal-neurological crises with cardiovascular symptoms, persistent paresis and transient respiratory paralysis.

دواعي الإستعمال

This test is useful in the diagnosis of ALA Dehydreatase Deficiency Porphyria, and intermittent severe acute hepatic porphyria syndrome, and is used as a marker of lead poisoning.

نوع العينة والكمية والشروط

30 ml of 24 Hrs Urine Room Temperature

إحتياطات خاصة

Instruct the patient to void at 8 a.m. and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (i.e., 8 a.m. the next morning). Measure and record total 24-hour urine volume.

المعدل الطبيعي

By Report

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