Coomb’s Test, Direct

Haemagglutination test in which antiglobulin, or anti-human globulin rabbit immune serum, is added to detect incomplete (non-agglutinating, univalent, blocking) antibodies coating erythrocytes. The direct test is applied to red cells which may have been coated with antibody in vivo.

Useful in the diagnosis of haemolytic disease of new-born, autoimmune haemolytic anaemia, and transfusion reactions. In addition, this test can be positive in association with certain drugs. The presence of potent cold autoagglutinins may interfere with test interpretation.

2 ml EDTA Whole Blood Room Temperature

Negative