Cytomegalovirus (CMV) Antibodies, IgG, Serum/Plasma

Human Cytomegalovirus (CMV) is the vernacular name of human herpesvirus 5, a highly host-specific virus of the Herpesviridae family. CMV, like all herpesviruses, undergoes latency and reactivation in the host and has been shown to infect a broad spectrum of cells in vivo. This virus can be a lifelong silent companion or a potential killer in organ transplant recipients, patients with AIDS, and cancer patients. The virus is kept at bay and its replication controlled by both the cellular and humoral arms of the immune system. Thus, Immuno-compromised individuals can experience cycles of viral reactivation. CMV is an important infectious agent responsible for mental retardation, intellectual impairment, and deafness in new-borns (congenital infection).

The detection of CMV specific IgG antibodies indicates recent or past infection with the virus.

1 ml Serum 1 ml K2, K3-EDTA, Na, Li-Heparin, Sodium Citrate, or Potassium Oxalate/Sodium Fluoride Plasma Stability: 14 Days at 2-8 °C > 14 Days at -10 °C or Colder

Avoid grossly haemolysed samples.

Non-Reactive: < 0.5 U/ml Intermediate: ≥ 0.5 - < 1.0 U/ml Reactive: ≥ 1.0 U/mL