Description
Eosinophil cationic protein (ECP), a weak ribonuclease and a potent neurotoxin, is one of four principal proteins found in eosinophil granules. Asthma is characterised by reversible airway obstruction, bronchial hyper-responsiveness, and airway inflammation. Eosinophilc inflammation of the lung is a factor underlying these abnormalities. Serum levels of ECP reflect the degree of activation of the circulating eosinophil pool in the body.
Indications
Serum ECP levels might refilect ongoing eosinophilic airway inflammation. However, serum ECP levels are not elevated in some patients with asthma, even when they are symptomatic.
Sample Type, Quantity & Conditions
2 ml Serum Room Temperature
Special Precautions
Leave blood for 60 -120 minutes before separating serum.
Normal Range
By Report
