High Density Lipoprotein (HDL) Cholesterol, Serum/Plasma


HDL is a class of heterogeneous lipoproteins containing approximately equal amounts of lipid (cholesterol) and protein (mainly Apolipoprotein A-1). HDL is involved in several metabolic functions including reverse cholesterol transport (removing cholesterol from peripheral tissues and delivering it to the liver and to steroidogenic organs), anti-oxidative mechanisms and endothelial function. See Also Cholesterol, Total, Serum


Low HDL is independently associated with increased risk for coronary disease. However, other genetic and acquired factors, may contribute to the the development of this disease.

Sample Type, Quantity & Conditions

1 ml Serum 1 ml K3-EDTA or Li, NH4+, and Na-Heparin Plasma Stability: 7 Days at 2-8 °C 30 Days at -70 °C

Special Precautions

12 hour fasting preferred.

Normal Range

Optimal: > 60 mg/dL > 1.55 mmol/L Borderline: 40 - 60 mg/dL 1.04 - 1.55 mmol/L Low: < 40 mg/dL < 1.04 mmol/L

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