Description
Thiamine is an active molecule and plays a part in many different aspects of energy metabolism that consists of a pyrimidine ring and a thiazolium ring joined by a methylene bridge.
Indications
The classical syndrome caused primarily by thiamine deficiency in humans is beriberi whose symptoms and signs may or may not be associated with oedema and vary according to the age of the patient. Its presentation also depends on the association with other vitamin deficiencies and the ingestion of empty calories, particularly in the form of simple carbohydrates. Thus, thiamine deficiency and beriberi are not synonymous terms, emphasising the importance of the interrelations of other nutrients with thiamine. Glyoxals are reactive α-oxoaldehydes that formed endogenously from sugars that are toxic towards hepatocytes, the levels of which are increased in various pathological conditions associated with hyperglycaemia and thiamine deficiency.
Sample Type, Quantity & Conditions
3 ml EDTA Whole Blood
Special Precautions
Protect from Light
Normal Range
10 - 64 ng/mL