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Contactin- 1 Antibodies, CSF

Description

Detects IgG autoantibodies to contactin-1, a paranodal axonal protein involved in certain autoimmune nodopathies.

Indications

Supports evaluation of chronic inflammatory demyelinating polyradiculoneuropathy/nodopathy variants, particularly with severe sensory ataxia, tremor, or poor response to standard therapy.

Sample Type, Quantity & Conditions

Serum

Special Precautions

Serum; avoid hemolysis/lipemia. Provide detailed neurologic phenotype and treatment history; paired CSF may be requested by the performing laboratory.

Normal Range

As per Report