Description
Anti CA15-3 antibodies are directed against epitopes expressed by a group of high molecular weight glycoproteins called polymorphic epithelia mucins, present in mammary epithelial cells and human milkfat globules.
Indications
CA 15-3 levels are increased in advanced breast carcinoma but not in benign breast disease or early breast carcinoma. CA 15-3 levels correlate with disease activity, progression, response to therapy and recurrence after therapy. Serum CA 15-3 is present in a small percentage of healthy females and males. Other conditions in which elevated CA15-3 have been reported include stomach, pancreas, bile duct, colon, thyroid, lung, cervical, endometrial, and ovarian cancer.
Sample Type, Quantity & Conditions
1 ml Serum 1 ml K3-EDTA or Li, Na-Heparin Stability: 7 Days at 2-8 °C > 7 Days at -20 °C
Special Precautions
Values obtained with different assay methods should not be used interchangeably.The same specimen, serum or plasma, should be used consistently when monitoring a patient. Avoid grossly haemolysed samples.
Normal Range
Up to 26.4 U/mL
