Description
Cell-based antibody testing for CASPR2, LGI1, and DPPX neural surface antibodies in CSF.
Indications
Evaluates suspected autoimmune encephalitis, limbic encephalitis, seizures, cognitive/psychiatric change, Morvan/neuromyotonia spectrum, or DPPX-associated hyperexcitability syndromes.
Sample Type, Quantity & Conditions
CSF
Special Precautions
Collect CSF aseptically in sterile polypropylene; avoid blood contamination. Paired serum is often important. Provide phenotype, MRI/EEG, and cancer history when available.
Normal Range
CASPR2 abs (IFT HEK 293 cells), CSF : < 1:1 Titer LG1 abs (IFT HEK 293 cells), CSF : < 1:1 Titer DPPX abs(IFT), CSF : < 1:1 Titer